Belinal ® Reduces Atherosclerotic Plaque Formation
Cardiovascular diseases are the leading cause of mortality and morbidity worldwide. One of the main underlying factors of these diseases is atherosclerosis, a chronic inflammatory condition that affects the arterial walls. Atherosclerosis is characterized by the accumulation of macrophages and oxidized low-density lipoproteins (LDL) in the subendothelial space, leading to plaque formation and narrowing of the arteries.. Atherosclerosis is a silent disease that can progress for decades without causing any symptoms, until it results in serious complications such as heart attack, stroke, or peripheral artery disease.
Belinal® is a natural product derived from the branch of silver fir (Abies alba), which has been shown to have potent antioxidant and anti-inflammatory properties. Belinal® acts on multiple mechanisms to prevent or reverse the functional and morphological changes in the arteries induced by atherosclerosis.
These mechanisms include:
- The unspecific effect of caloric restriction, which reduces the metabolic demand and the production of ROS.
- The influence on smooth muscle function, which modulates the vascular tone and the blood pressure, either directly or via the nitric oxide (NO) signaling pathway.
- The influence on the inflammation process, which inhibits the activation and migration of macrophages, the secretion of cytokines, and the expression of adhesion molecules and chemokines in the arterial wall.
- The prevention of lipoprotein oxidation, which reduces the formation and uptake of oxidized LDL by macrophages and the subsequent plaque development.
Diagram: The area of atherosclerotic plaques as the percent of the total area
In a recent animal study, we observed that Belinal® significantly reduced the atherosclerotic plaque formation by 80% in the aortas of rabbits fed with an atherogenic diet for 8 weeks. Moreover, Belinal® improved the relaxation response of the aortas by 37%, indicating a better endothelial function and vascular health. These results demonstrate that Belinal® effectively prevents the morphological and functional alterations of the arterial wall caused by atherosclerosis, and thus offers a promising natural solution for the protection of the arteries and the prevention of cardiovascular diseases.
Belinal® is a natural product derived from silver fir branches, rich in plant polyphenols that have anti-inflammatory and antioxidant properties. These polyphenols can help prevent and treat atherosclerosis, a condition that causes plaque build-up and narrowing of the arteries, leading to increased risk of heart disease and stroke. By taking Belinal® regularly, you can support your cardiovascular health and reduce the damage caused by oxidative stress and inflammation. Belinal® is a safe and effective way to improve your quality of life and well-being.